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Anti- AFP antibody (Detection Ab)

Catalog #BDA1025
Size1 mg
Price---
In stockYes
Datasheet MSDS
Overview
Catalog# BDA1025

Lot # Check on the product label


Size 1 mg


Isotype IgG1


Clone # C3


Host Mouse


Reactivity 
Human


Product Form Liquid


Purification & Buffer 
Protein A or G purified and supplied in 0.9% NaCl without preservative.


Purity >95% by HPLC & SDS-PAGE


Immunogen Recombinant Alpha fetal protein (AFP) protein.


Recommend Application
ELISA
Chemilumineseent immunoassay, CLIA
Other applications have not been tested.
The optimal dilutions should be determined by end user.


Matched antibody pair 
Capture Ab: AFP mAb (clone # A1)
Detection Ab: AFP mAb (clone # C3)


Storage Instruction 
Aliquot and store at -20°C for long term (at least one year).
Avoid repeated freeze and thaw cycles.


Background

Alpha-fetoprotein (AFP, α-fetoprotein; also sometimes called alpha-1-fetoprotein, alpha-fetoglobulin, or alpha fetal protein) is a protein that in humans is encoded by the AFP gene. The AFP gene is located on the q arm of chromosome 4 (4q25). Biological response evaluation by the measurement of serial AFP levels is a useful predictor of overall survival and intrahepatic remote recurrence after RFA. Therefore, an initial AFP response may aid in determining the need of closer follow-up as a therapeutic response indicator of RFA.


Reference

1. Yu SJ, Kwon JH, Kim W, Yoon JH, Lee JM, Lee JY, Cho EJ, Lee JH, Kim HY, Jung YJ, Kim YJ. Initial Alpha-Fetoprotein Response Predicts Prognosis in Hepatitis B-related Solitary HCC Patients After Radiofrequency Ablation. J Clin Gastroenterol. 2017 Aug 8.


Gene Information


Gene ID: 174
OMIM: 104150
Swiss Port: P02771