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Anti- BNP antibody (Capture Ab)

Catalog #BDA1028
Size1 mg
Price---
In stockYes
Datasheet MSDS
Overview
Catalog# BDA1028

Lot # Check on the product label


Size 1 mg


Isotype IgG2b


Clone # B4


Host Mouse


Reactivity

Human


Product Form Liquid


Purification & Buffer 
Protein A or G purified and supplied in 0.01 M PBS (pH7.4) without preservative.


Purity >95% by HPLC & SDS-PAGE


Immunogen Recombinant BNP protein.


Recommend Application
ELISA
Chemilumineseent immunoassay, CLIA
Other applications have not been tested.
The optimal dilutions should be determined by end user.


Matched antibody pair 
Capture Ab: BNP mAb (clone # B4)
Detection Ab: BNP mAb (clone # 2D6)


Storage Instruction 
Aliquot and store at -20°C for long term (at least one year).
Avoid repeated freeze and thaw cycles.


Background

Brain natriuretic peptide or B-type natriuretic peptide (BNP) (also ventricular natriuretic peptide or natriuretic peptide B) is a 32-amino acid polypeptide secreted by the ventricles of the heart in response to excessive stretching of heart muscle cells (cardiomyocytes). BNP is secreted attached to a 76–amino acid N-terminal fragment in the prohormone called NT-proBNP (BNPT), which is biologically inactive. BNP is synthesized as a 134-amino acid preprohormone (preproBNP), encoded by the human gene NPPB.


 Reference

1. Ziskoven D, Forssmann WG, Holthausen U, Menz G, Addicks K, Rippegater G (1989). "Calcium Calmodulin antagonists Influences the release of Cardiodilatin/ANP from Atrial Cardiocytes". In Kaufmann W, Wambach G. Handbook Endocrinology of the Heart. Berlin: Verlag: Springer. pp. 233–4.


Gene Information


Gene ID: 4879
OMIM: 600295
Swiss Port: P16860