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Anti- fFN antibody (Capture Ab)

Catalog #BDA1034
Size1 mg
Price---
In stockYes
Datasheet MSDS
Overview
Catalog# BDA1034

Lot # Check on the product label


Size 1 mg


Isotype IgG1


Clone # 1E5


Host Mouse


Reactivity 
Human


Product Form Liquid


Purification & Buffer 
Protein A or G purified and supplied in 0.01 M PBS (pH7.4) without preservative.


Purity >95% by HPLC & SDS-PAGE


Immunogen Native fetal fibronectin protein 


Recommend Application
ELISA
Chemiluminescence Assay, CLIA
Lateral flow assay (rapid test) 
Other applications have not been tested.
The optimal dilutions should be determined by end user.


Matched antibody pair 
Capture Ab: fFN mAb (clone # 1E5)
Detection Ab: fFN mAb (clone # A7)

It is recommended to use #1E5 & #A7 pair for Lateral flow assay (rapid test).


Storage Instruction 
Aliquot and store at -20°C for long term (at least one year).
Avoid repeated freeze and thaw cycles.


Background

Fetal fibronectin (fFN) is a fibronectin protein produced by fetal cells. It is found at the interface of the chorion and the decidua (between the fetal sac and the uterine lining). It can be thought of as an adhesive or "biological glue" that binds the fetal sac to the uterine lining. Fetal fibronectin "leaks" into the vagina if a preterm delivery is likely to occur and can be measured in a screening test. A false positive fetal fibronectin result can occur if the test is performed after digital examination of the cervix or after having had intercourse. It is important that the swab be taken before a digital vaginal exam is performed. 


Reference
1. Lockwood CJ, Senyei AE, Dische MR, et al. (1991). "Fetal fibronectin in cervical and vaginal secretions as a predictor of preterm delivery". N. Engl. J. Med. 325 (10): 669–74.


Gene Information


OMIM: 135600
Swiss Port: P02751
Gene ID: 2335