Overview

Catalog# BMA1004

Lot # Check on the product label

Size 100μg

Isotype IgG2b

Clone # D38-6

Host Mouse

Reactivity
Human

Product Form Liquid

Purification Protein A or Protein G purified

Immunogen
A synthetic peptide (conjugated with KLH) corresponding to the region of human PLAP-1.

Recommend Application
Western Blot (1:5000-10000)
Immunocytochemistry, ICC (1:100)
Immunohistochemistry, IHC-P (1:200)
Other applications have not been tested.
 The optimal dilutions should be determined       by end user.

Storage Buffer
In TBS (pH7.4), 0.5% BSA, 25% Glycerol and 0.05% Sodium Azide.

Storage Instruction
Store at 4°C after thawing (1 week). Aliquot and store at -20°C for long term (at least one year).
Avoid repeated freeze and thaw cycles.

Background
Alkaline phosphatase, placental type also known as placental alkaline phosphatase (PLAP) is an allosteric enzyme that in humans is encoded by the ALPP gene. It is a membrane bound glycosylated dimeric enzyme, also referred to as the heat stable form, that is expressed primarily in the placenta although it is closely related to the intestinal form of the enzyme as well as to the placental-like form.¹ Placental alkaline phosphatase is also present in extracts of liver and intestine in appreciable amounts.²

Reference
1. "Entrez Gene: ALPP alkaline phosphatase, placental (Regan isozyme)"
2. Garattini, E., Margolis, J., Heimer, E., Felix, A., Udenfriend, S. Human placental alkaline phosphatase in liver and intestine. Proc. Nat. Acad. Sci. 82: 6080-6084, 1985. 

Gene Information

OMIM:171800
Swiss Port:P05187
Gene ID:250