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Anti- ALPP/ALAP antibody
Overview
Catalog# BPA1007
Lot # Check on the product label
Size 100 μg
Isotype IgG
Host Rabbit
Reactivity
Human
Product Form Liquid
Purification Immunogen affinity purified
Immunogen
A synthetic peptide (conjugated with KLH) corresponding to the region of human ALPP.
Recommend Application
Western Blot, WB (1:50-1:2000)
Other applications have not been tested.
The optimal dilutions should be determined by end user.
Storage Buffer
1*PBS (pH7.4), 0.2% BSA, 40% Glycerol and 0.05% Sodium Azide.
Storage Instruction
Store at 4°C after thawing (1 week). Aliquot and store at -20°C for long term (at least one year).
Avoid repeated freeze and thaw cycles.
Store at 4°C after thawing (1 week). Aliquot and store at -20°C for long term (at least one year).
Avoid repeated freeze and thaw cycles.
Background
Alkaline phosphatase, placental type also known as placental alkaline phosphatase (PLAP) is an allosteric enzyme that in humans is encoded by the ALPP gene. It is a membrane bound glycosylated dimeric enzyme, also referred to as the heat stable form, that is expressed primarily in the placenta although it is closely related to the intestinal form of the enzyme as well as to the placental-like form.1 Placental alkaline phosphatase is also present in extracts of liver and intestine in appreciable amounts.2
Alkaline phosphatase, placental type also known as placental alkaline phosphatase (PLAP) is an allosteric enzyme that in humans is encoded by the ALPP gene. It is a membrane bound glycosylated dimeric enzyme, also referred to as the heat stable form, that is expressed primarily in the placenta although it is closely related to the intestinal form of the enzyme as well as to the placental-like form.1 Placental alkaline phosphatase is also present in extracts of liver and intestine in appreciable amounts.2
Reference
1. "Entrez Gene: ALPP alkaline phosphatase, placental (Regan isozyme)"
2. Garattini, E., Margolis, J., Heimer, E., Felix, A., Udenfriend, S. Human placental alkaline phosphatase in liver and intestine. Proc. Nat. Acad. Sci. 82: 6080-6084, 1985.
1. "Entrez Gene: ALPP alkaline phosphatase, placental (Regan isozyme)"
2. Garattini, E., Margolis, J., Heimer, E., Felix, A., Udenfriend, S. Human placental alkaline phosphatase in liver and intestine. Proc. Nat. Acad. Sci. 82: 6080-6084, 1985.
Gene Information
OMIM:171760
Swiss Port: P05186
Gene ID: 249
