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Monoclonal Anti- Histone H3.1 antibody

Catalog #BTL1033
Size0.1ml
Price---
In stockYes
Datasheet MSDS

Overview


Catalog# BTL1033



Lot # Check on the product label



Size 100μg



Isotype IgG1



Host Mouse



Reactivity
Human, mouse, rat



Product Form Liquid (1mg/ml)



Immunogen
Human Histone H3.1 protein with full length.



Recommend Application
Western Blot (1:1000-10000)
 Other applications have not been tested.
 The optimal dilutions should be determined       by end user.



Storage Buffer
In PBS (pH7.4), 50% Glycerol and 0.02% Sodium Azide.



Storage Instruction
Store at -20°C for 1 year.
Avoid repeated freeze and thaw cycles.



Background
Histone H3.1 is a protein that in humans is encoded by the HIST1H3C gene. Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes.



Reference
1. Kardalinou E, Eick S, Albig W, Doenecke D (Dec 1993). "Association of a human H1 histone gene with an H2A pseudogene and genes encoding H2B.1 and H3.1 histones". J Cell Biochem 52 (4): 375–83.
2. Albig W, Kioschis P, Poustka A, Meergans K, Doenecke D (Apr 1997). "Human histone gene organization: nonregular arrangement within a large cluster". Genomics 40 (2): 314–22.
3. Marzluff WF, Gongidi P, Woods KR, Jin J, Maltais LJ (Oct 2002). "The human and mouse replication-dependent histone genes". Genomics 80 (5): 487–98.