Polyclonal Anti- Transmembrane protein 132E, TMEM132E Antibody

Catalog#  BPA1105

Lot # Check on the product label

Size 100 μg

Isotype IgG 

Host Rabbit

Reactivity Human, mouse

Product Form Liquid

Purification Immunogen affinity purified

Immunogen 

A synthetic peptide (conjugated with KLH) corresponding to the region of TMEM132E.

Recommend Application

Western Blot, WB (1:100-200)

Other applications have not been tested.

The optimal dilutions should be determined by end user.

Storage Buffer

1*PBS (pH7.4), 0.2% BSA, 40% Glycerol and 0.05% Sodium Azide.

Storage Instruction 

Store at 4°C after thawing (1 week). Aliquot and store at -20°C for long term (at least one year).

Avoid repeated freeze and thaw cycles.

Background

Transmembrane protein 132E (TMEM132E) also known as HSPA5-binding protein 1, is a member of the TMEM132 family, which composed of TMEM132A, -B, -C, -D, -E. It is located in a region involved in a heterozygous deletion of approximately 4.7 Mb, this deletion, involving the NF1 gene and contiguous genes lying in its flanking regions, is observed in a patient 17q11.2 microdeletion syndrome, a syndrome characterized by variable facial dysmorphism, mental retardation, developmental delay, and an excessive number of neurofibromas.

Reference

1. "Heterogeneity of breakpoints in non-LCR-mediated large constitutional deletions of the 17q11.2 NF1 tumour suppressor region."Kehrer-Sawatzki H., Tinschert S., Jenne D.E.J. Med. Genet. 40:E116-E116(2003)