Monoclonal Anti- Alkaline Phosphatase (placental & placental-like), PLAP Antibody

CatalogNo.: BMA1004
Size: 100 μg
Host: Mouse
Reactivity: Human, mouse
Isotype: IgG
Application: WB, IHC-P, ICC
--------------------------------------------------------------------------------------------------------------
Price: $180.00

  


Catalog# BMA1004


Lot # Check on the product label


Size 100 μg


Isotype IgG2b


Clone # D38-6


Host Mouse


Reactivity Human, mouse


Product Form Liquid


Purification Protein A purified


Immunogen 

A synthetic peptide (conjugated with KLH) corresponding to the region of human PLAP-1.


Recommend Application

Western Blot, WB (1:2000-5000)

Immunohistochemistry, IHC-P (1:100)

Immunocytochemistry, ICC (1:50)

Other applications have not been tested.

The optimal dilutions should be determined by end user.

Storage Buffer

1*PBS (pH7.4), 0.2% BSA, 40% Glycerol and 0.05% Sodium Azide.

Storage Instruction 

Store at 4°C after thawing (1 week). Aliquot and store at -20°C for long term (at least one year).

Avoid repeated freeze and thaw cycles.


Background

Alkaline phosphatase, placental type also known as placental alkaline phosphatase (PLAP) is an allosteric enzyme that in humans is encoded by the ALPP gene. It is a membrane bound glycosylated dimeric enzyme, also referred to as the heat stable form, that is expressed primarily in the placenta although it is closely related to the intestinal form of the enzyme as well as to the placental-like form. Placental alkaline phosphatase is also present in extracts of liver and intestine in appreciable amounts.


Reference

1. "Entrez Gene: ALPP alkaline phosphatase, placental (Regan isozyme)"

2. Garattini, E., Margolis, J., Heimer, E., Felix, A., Udenfriend, S. Human placental alkaline phosphatase in liver and intestine. Proc. Nat. Acad. Sci. 82: 6080-6084, 1985.

Details