Recombinant human hepatitis C virus, HCV Protein (Detection)

Catalog# BRP1143

Lot # Check on the product label

Size 1 mg

Description

Recombinant human hepatitis C virus, HCV Protein from E.coli.

Synonyms Hepatitis C virus, HCV, human hepatitis C virus

Source E.coli

Purity >95% by SDS-PAGE

Purification Affinity purified

Formulation Liquid

Application

Lateral flow

ELISA

Other applications have not been tested. 

The optimal dilutions should be determined by end user.

Matched pairs

Capture: BRP1142

Detection: BRP1143

Storage buffer

Each vial contains 0.01 M PBS (pH7.4).

Storage & Expiration

Ship at 4℃. Upon receipt, aliquot and store at -20℃ for long term.

Avoid repeated freeze and thaw cycles.

Background

The hepatitis C virus (HCV) is a small (55–65 nm in size), enveloped, positive-sense single-stranded RNA virus of the family Flaviviridae. The hepatitis C virus is the cause of hepatitis C and some cancers such as liver cancer (hepatocellular carcinoma, abbreviated HCC) and lymphomas in humans. The hepatitis C virus particle consists of a lipid membrane envelope that is 55 to 65 nm in diameter. Two viral envelope glycoproteins, E1 and E2, are embedded in the lipid envelope. They take part in viral attachment and entry into the cell. Within the envelope is an icosahedral core that is 33 to 40 nm in diameter. Inside the core is the RNA material of the virus.

Reference

1. Ferri, Clodoveo (2015). "HCV syndrome: A constellation of organ- and non-organ specific autoimmune disorders, B-cell non-Hodgkin's lymphoma, and cancer". World Journal of Hepatology. 7 (3): 327–43.

2. Dubuisson, Jean; Cosset, François-Loïc (2014). "Virology and cell biology of the hepatitis C virus life cycle – An update". Journal of Hepatology. 61 (1): S3–S13.