Recombinant Plasmodium vivax-lactate dehydrogenase, Pv-LDH Protein

Catalog# BRP1144

Lot # Check on the product label

Size 100 µg

Description

Recombinant Pv-LDH Protein with His tag.

Source E.coli

Purity >95% by SDS-PAGE

Purification Affinity purified

Formulation Liquid

Molecular Weight  35kDa

Application

Immunoassays

Other applications have not been tested. 

The optimal dilutions should be determined by end user.

Storage buffer

Each vial contains 0.01 M PBS (pH7.8) and 0.1% Proclin300.

Storage & Expiration

Ship at 4℃. Upon receipt, aliquot and store at -20℃ for long term.

Avoid repeated freeze and thaw cycles.

Background

Malaria caused by Plasmodium vivax is a major cause of global morbidity and, in rare cases, mortality. Lactate dehydrogenase is an essential Plasmodium protein and, therefore, a potential antimalarial drug target. Ideally, drugs directed against this target would be effective against both major species of Plasmodium, P. falciparum and P. vivax.

Reference

1. Balamurugan Sundaram, Nandan Mysore Varadarajan, Pradeep Annamalai Subramani, Susanta Kumar Ghosh, Viswanathan Arun Nagaraj. Purification of a recombinant histidine-tagged lactate dehydrogenase from the malaria parasite, Plasmodium vivax, and characterization of its properties. Biotechnology Letters 2014, 36 (12) , 2473-2480.