Recombinant Monkeypox Virus, MPXV A29 Protein

Catalog# BRP1145

Lot # Check on the product label

Size 100 μg

Description

Recombinant monkey MPXV A29 protein with his tag.

Source E. Coli

Purity >95% by SDS-PAGE

Purification Affinity purification

Formulation Liquid

Concentration 1.5 mg/ml

Molecular Weight 13.9kDa

Application

EIA

Other applications have not been tested.

The optimal dilutions should be determined by end user.

Storage buffer

0.01M PBS, 0.3M Nacl, pH 7.4, 0.1% Proclin300

Storage & Expiration

Ship at 4℃. Upon receipt, aliquot and store at -20℃ or -80℃ for long term.

Avoid repeated freeze and thaw cycles.

Background

Monkeypox virus (MPV or MPXV) is a double-stranded DNA virus that causes monkeypox in humans and other animals. It belongs to the genus Orthopoxvirus in the family Poxviridae. It is one of the human orthopoxviruses that includes variola (VARV), cowpox (CPX), and vaccinia (VACV) viruses. It is not a direct ancestor to, nor a direct descendant of, the variola virus, which causes smallpox. Monkeypox disease is similar to smallpox, but with a milder rash and lower mortality rate. Variation in virulence of the virus has been observed in isolates from Central Africa, where strains are more virulent than those from Western Africa. The two areas have distinct clades of the virus, termed Congo Basin (Central African) and West African clades.

Reference

1. Breman JG, Kalisa R, Steniowski MV, Zanotto E, Gromyko AI, Arita I (1980). "Human monkeypox, 1970-79". Bull World Health Organ. 58 (2): 165–182.

2. Alkhalil Abdulnaser; Hammamieh Rasha; Hardick Justin; Ichou Mohamed A; Jett Marti; Ibrahim Sofi (2010). "Gene expression profiling of monkeypox virus-infected cells reveals novel interfaces for host-virus interactions". Virology Journal. 7: 173.

3. Shchelkunov SN, Totmenin AV, Safronov PF, Mikheev MV, Gutorov VV, Ryazankina OI, Petrov NA, Babkin IV, Uvarova EA, Sandakhchiev LS, et al. (2002).