Ferritin Protein (Active)

Catalog# BNP1015

Lot # Check on the product label

Size 1 mg

Description

Purified human Ferritin protein.

Source Human liver

Purity >60% by SDS-PAGE

Formulation Liquid

Concentration 1 mg/ml

Application

ELISA

Other applications have not been tested.

Storage buffer

Each vial contains 0.01 M PBS (pH 7.4) with 0.05% NaN_3.

Storage & Expiration

Ship at 4℃. Upon receipt, aliquot and store at -20℃ or -80℃ for long term.

Avoid repeated freeze and thaw cycles.

Background

Ferritin is a ubiquitous intracellular protein that stores iron and releases it in a controlled fashion. It is a protein of 450 kDa consisting of 24 subunits that is present in every cell type. In vertebrates, these subunits are both the light (L) and the heavy (H) type with an apparent molecular weight of 19 kDA or 21 kDA respectively; their sequences are about 50% homologous. Ferritin plays a key role in cellular iron metabolism, which includes iron storage and detoxification. It also plays a role in the haemolymph of the polyplacophora where it serves to rapidly transport iron to the mineralizing radula.

Reference

1. Theil, E. (1987). "Ferritin: structure, gene regulation, and cellular function in animals, plants, and microorganisms.". Annual review of biochemistry 56 (1): 289–315.

2. De Zoysa, M.; Lee, J. (2007). "Two ferritin subunits from disk abalone (Haliotis discus discus): cloning, characterization and expression analysis.". Fish & shellfish immunology 23 (3): 624–635.

3. Kyungsukkim; Webb, J.; Macey, D. (1986). "Properties and role of ferritin in the hemolymph of the chiton Clavarizona hirtosa". Biochimica et Biophysica Acta (BBA) - General Subjects 884 (3): 387.