Monoclonal Anti- Brain natriuretic peptide, BNP (Detection Ab) Antibody
Size: 1mg
Host: Mouse
Reactivity: Human
Isotype: IgG2b
Application: ELISA, CLIA, FFIA
--------------------------------------------------------------------------------------------------------------
Price: $350.00
Catalog# BDA1029
Lot # Check on the product label
Size 1 mg(5.28 mg/ml)
Isotype IgG2b
Clone # 2D6
Host Mouse
Reactivity
Human
Product Form Liquid
Purification & Buffer
Protein A or G purified and supplied in 0.01 M PBS (pH7.4) without preservative.
Purity>95% by HPLC & SDS-PAGE
Immunogen Recombinant BNP protein.
Recommend Application
ELISA
Chemilumineseent immunoassay, CLIA
Flow Fluorenscence Immunmicrobeads Assay, FFIA
Other applications have not been tested.
The optimal dilutions should be determined by end user.
Matched antibody pair
Capture Ab: BNP mAb (clone # B4)
Detection Ab: BNP mAb (clone # 2D6)
Storage Instruction
Aliquot and store at -20°C for long term (at least one year).
Avoid repeated freeze and thaw cycles.
Background
Brain natriuretic peptide or B-type natriuretic peptide (BNP) (also ventricular natriuretic peptide or natriuretic peptide B) is a 32-amino acid polypeptide secreted by the ventricles of the heart in response to excessive stretching of heart muscle cells (cardiomyocytes). BNP is secreted attached to a 76–amino acid N-terminal fragment in the prohormone called NT-proBNP (BNPT), which is biologically inactive. BNP is synthesized as a 134-amino acid preprohormone (preproBNP), encoded by the human gene NPPB.
Reference
1. Ziskoven D, Forssmann WG, Holthausen U, Menz G, Addicks K, Rippegater G (1989). "Calcium Calmodulin antagonists Influences the release of Cardiodilatin/ANP from Atrial Cardiocytes". In Kaufmann W, Wambach G. Handbook Endocrinology of the Heart. Berlin: Verlag: Springer. pp. 233–4.