Monoclonal Anti- Interleukin 1 receptor-like 1, IL1RL1/ST2 (Detection Ab) Antibody

Catalog# BDA1044

Lot # Check on the product label

Size 1 mg

Isotype IgG1

Clone # 2E5

Host Mouse

Reactivity Human

Product Form Liquid

Purification & Buffer

Protein A or G purified and supplied in 0.9% NaCl without preservative.

Purity >95% by HPLC & SDS-PAGE

Immunogen Recombinant human IL-1RL1/ST2 Protein.

Recommend Application

ELISA

Chemilumineseent immunoassay, CLIA

Other applications have not been tested.

The optimal dilutions should be determined by end user.

Matched antibody pair

Capture Ab: ST2 mAb (clone # 1A9)

Detection Ab: ST2 mAb (clone # 2E5)

Storage Instruction 

Aliquot and store at -20°C for long term (at least one year).

Avoid repeated freeze and thaw cycles.

Background

Interleukin 1 receptor-like 1, also known as IL1RL1 and ST2, is a protein that in humans is encoded by the IL1RL1 gene. ST2 is a member of the interleukin 1 receptor family. The ST2 protein has two isoforms and is directly implicated in the progression of cardiac disease: a soluble form (referred to as soluble ST2 or sST2) and a membrane-bound receptor form (referred to as the ST2 receptor or ST2L).  

Reference

1. "Entrez Gene: IL1RL1 interleukin 1 receptor-like 1"

2. Tominaga S, Yokota T, Yanagisawa K, Tsukamoto T, Takagi T, Tetsuka T (December 1992). "Nucleotide sequence of a complementary DNA for human ST2". Biochim. Biophys. Acta. 1171 (2): 215–8.

3. Dale M, Nicklin MJ (April 1999). "Interleukin-1 receptor cluster: gene organization of IL1R2, IL1R1, IL1RL2 (IL-1Rrp2), IL1RL1 (T1/ST2), and IL18R1 (IL-1Rrp) on human chromosome 2q". Genomics. 57 (1): 177–9.