Monosialotetrahexosylganglioside Sodium Salt, GM1

Catalog No.: BRX1001

Size: gram (Flexible sizes for choice, please inquiry for bulk)

Molecular formula C₇₃H₁₃₀N₃NaO₃₁ or C₇₅H₁₃₄N₃NaO₃₁

Molecular weight 1568.84 or 1597.18

Source Purified from porcine brain

Product form White powder

Purity >99%

Quality Bulk pharmaceutical chemicals (Injection Grade)

Storage Store at room temperature in dark

Introduction

GM1 (monosialotetrahexosylganglioside) the "prototype" ganglioside, is a member of the ganglio series of gangliosides which contain one sialic acid residue. GM1 has important physiological properties and impacts neuronal plasticity and repair mechanisms, and the release of neurotrophins in the brain. Besides its function in the physiology of the brain, GM1 acts as the site of binding for both Cholera toxin and E. coli heat-labile enterotoxin (Traveller's diarrhea).

Reference

1. Mocchetti I (2005). "Exogenous gangliosides, neuronal plasticity and repair, and the neurotrophins". Cell. Mol. Life Sci. 62 (19–20): 2283–94.

2. Chen JC, Chang YS, Wu SL, et al. (September 2007). "Inhibition of Escherichia coli heat-labile enterotoxin-induced diarrhea by Chaenomeles speciosa". J Ethnopharmacol 113 (2): 233–9.