Monoclonal Anti- Sulfadiazine Antibody

Catalog# BDA1020

Lot # Check on the product label

Size 1mg

Host Mouse

Product Form Liquid

Concentration 4 mg/ml (Changed for different lots)

Purification & Buffer

Protein A or G purified and supplied in 0.01 M PBS (pH7.4)

Purity >95% by HPLC & SDS-PAGE

IC50 Value

0.5-1.2 ppb

Sensitivity 4 ppb

Recommend Application

ELISA (1:100000)

Other applications have not been tested.

The optimal dilutions should be determined by end user.

Storage Instruction 

Aliquot and store at -20°C for 2 years. 

Avoid repeated freeze and thaw cycles.

Background

Sulfadiazine is a sulfonamide antibiotic. It eliminates bacteria that cause infections by stopping the production of folate inside the bacterial cell, and is commonly used to treat urinary tract infections. Antibiotics and heavy metals often coexist in soils due to land application of animal wastes and other sources of inputs. Xu Y et al evaluated the interaction of Cu(II) and sulfadiazine (SDZ) regarding to their sorption and desorption on Brown soil (BS, luvisols) and Red soil (RS, Udic Ferrosols) using batch experiments. The results indicate that soil characteristics strongly influence the interactions of Cu(II) and SDZ on their sorption and desorption on soils. Mavrodinova V et al found that if sulfadiazine (SD) was loaded in solution, part of the zeolite silver ions was released and interacted with SD, forming AgSD. By solid-state SD deposition, the reaction between the drug and the silver was restricted within the limits of inter-atomic interaction, and total but prolonged drug release occurred.

Reference

1. Xu Y, Yu W, Ma Q, Zhou H. Interactive effects of sulfadiazine and Cu(II) on their sorption and desorption on two soils with different characteristics. Chemosphere. 2015 Nov;138:701-7.

2. Mavrodinova V, Popova M, Yoncheva K, Mihály J, Szegedi Á. Solid-state encapsulation of Ag and sulfadiazine on zeolite Y carrier. J Colloid Interface Sci. 2015 Nov 15;458:32-8.