Recombinant Rabbit Monoclonal Anti- Moesin antibody

Catalog#  BRM1132-1

Lot # Check on the product label

Size 50 μl

Isotype IgG

Host Rabbit

Reactivity 

Human, mouse, rat

Immunogen A synthetic peptide of human Moesin.

Clone ID  4D17

Synonyms Villin 2 ezrin; CVIL; CVL; Cytovillin 2; Cytovillin; EZR; Ezrin; p81; VIL 2; VIL2; Villin 2 (ezrin); Villin 2; Villin-2; Villin2; HEL70; Membrane-organizing extension spike protein; Moesin/anaplastic lymphoma kinase fusion protein; Msn; MSN/ALK fusion; HIB; Moesin-B; Protein roadkill; Radixin; RDX

Content Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.

Recommend Application

Western Blot, WB (1:1000)

Immunohistochemistry, IHC-P (1:50)

Immunoprecipitation, IP (1:20)

Immunocytochemistry, ICC/IF (1:50)

Other applications have not been tested.

The optimal dilutions should be determined by end user.

Storage Instruction 

Ship at 2-8°C, when receipt, aliquot and store at -20°C for one year.

Avoid repeated freeze and thaw cycles.

Background

Moesin is a protein that in humans is encoded by the MSN gene. Moesin (for membrane-organizing extension spike protein) is a member of the ERM protein family which includes ezrin and radixin. ERM proteins appear to function as cross-linkers between plasma membranes and actin-based cytoskeletons. Moesin is localized to filopodia and other membranous protrusions that are important for cell–cell recognition and signaling and for cell movement. Moesin has FERM domain at N-terminal.

Reference

1. Lankes WT, Furthmayr H (Oct 1991). "Moesin: a member of the protein 4.1-talin-ezrin family of proteins". Proc. Natl. Acad. Sci. U.S.A. 88 (19): 8297–301. Bibcode:1991PNAS...88.8297L.

2. Amieva MR, Furthmayr H (Sep 1995). "Subcellular localization of moesin in dynamic filopodia, retraction fibers, and other structures involved in substrate exploration, attachment, and cell-cell contacts". Exp. Cell Res. 219 (1): 180–96.