Recombinant Rabbit Monoclonal Anti- Histone H1.2 antibody
|
Catalog# |
BRM1134-2 |
|---|---|
|
Lot # |
Check on the product label |
|
Size |
100 μl |
| Isotype |
IgG |
| Host | Rabbit |
|
Reactivity |
Human, mouse, rat |
| Immunogen | A synthetic peptide of human Histone H1.2. |
|
Clone ID |
9S17 |
| Synonyms | H1 histone family member 2; H1.a; H1F2; H1s-1; HIST1H1C; Histone 1 H1c; Histone cluster 1 H1c; Histone H1c; Histone H1d; Histone H1s-1 |
| Content | Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA. |
| Recommend Application |
Western Blot, WB (1:1000-5000) The optimal dilutions should be determined by end user. |
| Storage Instruction | Ship at 2-8°C, when receipt, aliquot and store at -20°C for one year. Avoid repeated freeze and thaw cycles. |
|
Background |
Histone H1 protein binds to linker DNA between nucleosomes forming the macromolecular structure known as the chromatin fiber. Histones H1 are necessary for the condensation of nucleosome chains into higher-order structured fibers. Acts also as a regulator of individual gene transcription through chromatin remodeling, nucleosome spacing and DNA methylation. |
|
Reference |
1. Marthandan S et al. Conserved Senescence Associated Genes and Pathways in Primary Human Fibroblasts Detected by RNA-Seq. PLoS One 11:e0154531 (2016). |
