Recombinant Human PDCD5 Protein

BRP1200-2

Check on the product label

50 μg

Recombinant human PDCD5 is produced by the E.coli system, with the target gene encoding Met1-Tyr125 expressed with 6x His-tag at the C-terminus.

E.coli

O14737

>95% by SDS-PAGE

Lyophilized from a 0.2 μm filtered solution of 20 mM Tris-HCl, 5% Sucrose, 5% Mannitol, 50 mM NaCl, 0.05% Tween 80, pH 8.4.

Dissolve the lyophilized protein in distilled water (It is not recommended to reconstitute to a concentration <100 μg/ml.)

SDS-PAGE

Other applications have not been tested.

The optimal dilutions should be determined by end user.

Ship at 4℃. Upon receipt, aliquot and store at -20℃ or -80℃ for long term.

Avoid repeated freeze and thaw cycles.

Programmed cell death protein 5 is a protein, originally identified as an apoptosis-accelerating protein, that in humans is encoded by the PDCD5 gene. This gene encodes a protein expressed in tumor cells during apoptosis independent of the apoptosis-inducing stimuli. Prior to apoptosis induction, this gene product is distributed in both the nucleus and cytoplasm. Once apoptosis is induced, the level of this protein increases and by relocation from the cytoplasm, it accumulates in the nucleus. Although its exact function is not defined, this protein is thought to play an early and universal role in apoptosis.

1. Li G, Ma D, Chen Y (April 2016). "Cellular functions of programmed cell death 5". Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 1863 (4): 572–580.

2. Liu H, Wang Y, Zhang Y, Song Q, Di C, Chen G, Tang J, Ma D (January 1999). "TFAR19, a novel apoptosis-related gene cloned from human leukemia cell line TF-1, could enhance apoptosis of some tumor cells induced by growth factor withdrawal". Biochemical and Biophysical Research Communications. 254 (1): 203–210.